Searchable abstracts of presentations at key conferences in endocrinology

ea0019oc7 | Young Endocrinologist prize session | SFEBES2009

In vivo and ex vivo regulation of Visfatin production by leptin in human and murine adipose tissue: role of the PI3K and MAPK pathways

Tan Bee , Chen Jing , Brown James , Adya Raghu , Ramanjaneya Manjunath , Bailey Cliff , Lehnert Hendrik , Randeva Harpal

Apart from its role in energy storage, adipose tissue produces several hormones and cytokines termed ‘adipokines’ that have wide-ranging effects on carbohydrate and lipid metabolism; and thereby, play an important role in the pathogenesis of the metabolic syndrome. Visfatin is a novel adipokine, levels of which increase in obesity and is adipogenic; properties common to that of leptin. Thus, leptin may modulate visfatin production in adipose tissue. We investigated t...